UPC: 9783030873233 | Springerbriefs in Microbiology: Sars-Cov-2 Spike Protein Convergent Evolution: Impact of Virus Variants on Efficacy of Covid-19 Therapeutics and Vaccines (Paperback)
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UPC lookup results for: 9783030873233 | Springerbriefs in Microbiology: Sars-Cov-2 Spike Protein Convergent Evolution: Impact of Virus Variants on Efficacy of Covid-19 Therapeutics and Vaccines (Paperback)
Why the Spike protein is relevant for COVID19 therapeutics Whole genome mutation rates Phylogenetic systems Mechanism of immune escape: single nucleotide mutations insertion/deletions and recombination. Spike protein mutations detected in currently circulating strains. SARS-CoV-2 variants B.1.1.298 B.1.1.7 (alpha) B.1.351 (beta) B.1.1.28- and B.1.1.33-derived Brazilian variants (including gamma and zeta) B.1.525 (eta) B.1.526 (iota) B.1.427/B.1.429 (epsilon) B.1.617-derived variants (including kappa and delta) B.1.617.1 Delta VOC C.37 (lambda) P.3 (theta) Other variants under monitoring (VUM) Which strain will finally become dominant? SARS-CoV-2 variants characterization Predicting the functional consequences of mutations Efficacy of vaccines and monoclonal antibodies against SARS-CoV-2 variants Selective pressures exerted by antibody-based therapeutics
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