UPC: 9781588293190 | Contemporary Immunology: Neonatal Immunity (Hardcover)
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UPC lookup results for: 9781588293190 | Contemporary Immunology: Neonatal Immunity (Hardcover)
A critical review of the classic as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how in certain cases this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants compared to those of adults Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens.
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